Lineas de investigacion

Quality and functionality of plant foods (BIOACTIVEG)

Description

Objetives

Chemical and biochemical characterization of plant foods (fresh and processed) and their components by advanced analytical methods. Study of the biological activity and functionality of plant foods by using in vitro studies (simulated gastrointestinal digestion and cell culture) and in vivo studies (studies in animal models and human intervention studies). Study of the effect of food processing and preservation technologies on bioactive compounds, their bioaccessibility and bioavailability, by means of in vitro and in vivo studies.

Research Lines

  • Quality and functionality of plant foods and their constituents
  • Biological activity and functionality of plant foods.
  • New foods and functional ingredients.
  • Processing technologies and bioactive compounds
Capacidades

Skills

  • Evaluation of the nutritional quality and functionality of plant foods, fresh or processed, using advanced analytical techniques like GC / MS, HPLC-DAD/MS, LC / MS Q-TOF, etc., as a support for the study of metabolites (metabolomics), markers of biological activity of such foods.
  • Design of new plant foods and functional ingredients by high hydrostatic pressure and minimal processing techniques.
  • Evaluation of biological activity of phytochemicals in plant foods, including bioaccessibility and bioavailability studies, using in vitro techniques (gastrointestinal digestion patterns combined with cell culture studies) and in vivo studies using animal models and humans intervention studies.

Personnel

Group Leader:

Members:

Contact:

  • 91 549 23 00
  • ancos@ictan.csic.es
  • csanchezm@ictan.csic.es

Keywords

Plant foods,Biological activity, Functional foods, Processing, High-pressure, Bioaccessibility

Publications

  • Fernández-Jalao I, Balderas C, Sánchez-Moreno C, de Ancos B. Impact of an in vitro dynamic gastrointestinal digestion on phenolic compounds and antioxidant activity of apple treated by high-pressure processing. Innovative Food Science & Emerging Technologies, 66, 102486, 2020. https://doi.org/10.1016/j.ifset.2020.102486
  • Fernández-Jalao I, Sánchez-Moreno C, de Ancos B. Effect of high-pressure processing on flavonoids, hydroxycinnamic acids, dihydrochalcones and antioxidant activity of apple ‘Golden Delicious’ from different geographical origin. Innovative Food Science & Emerging Technologies, 51, 20-31, 2019. https://doi.org/10.1016/j.ifset.2018.06.002
  • Fernández-Jalao I, Sánchez-Moreno C, de Ancos B. Influence of food matrix and high-pressure processing on onion flavonols and antioxidant activity during gastrointestinal digestion. Journal of Food Engineering, 213, 60-68, 2017. https://doi.org/10.1016/j.jfoodeng.2017.02.015
  • Colina-Coca C, González-Peña D, de Ancos B, Sánchez-Moreno C. Dietary onion ameliorates antioxidant defence, inflammatory response, and cardiovascular risk biomarkers in hypercholesterolemic Wistar rats. Journal of Functional Foods, 36, 300-309, 2017. https://doi.org/10.1016/j.jff.2017.07.014
  • González-Peña D, Checa A, de Ancos B, Wheelock CE, Sánchez-Moreno C. New insights into the effects of onion consumption on lipid mediators using a diet-induced model of hypercholesterolemia. Redox Biology, 11, 205-212, 2017. https://doi.org/10.1016/j.redox.2016.12.002
  • González-Peña D, Dudzik D, Colina-Coca C, de Ancos B, García A, Barbas C, Sánchez-Moreno C. Multiplatform metabolomic fingerprinting as a tool for understanding hypercholesterolemia in Wistar rats. European Journal of Nutrition, 55(3), 997-1010, 2016. https://doi.org/10.1007/s00394-015-0914-1

Projects, Contracts, Agreements

FEDER projects

Influence of matrix and processing on the metabolism and prebiotic effect of natural phenolic compounds in a dynamic gastrointestinal model

Main Researcher: B. de Ancos / Start Date: 01/01/2014 / End Date: 12/31/2016 / Institution: MINECO/ERDF, EU / Reference number: AGL2013-46326-R
Research Group: Quality and functionality of plant foods (BIOACTIVEG)


Valorization of Mango and Apple By-products and Wastes as Source of Cytoprotective and Antiinflammatory Encapsulated Bioactive Compounds.

Main Researcher: B. de Ancos and C. Sánchez-Moreno. / Start Date: 06/01/2020 / End Date: 05/31/2023 / Institution: MCIU/AEI/ERDF, EU / Reference number: PID2019-107980RB-I00
Research Group: Quality and functionality of plant foods (BIOACTIVEG)


Effect of plant functional food ingredients on inflammatory response, oxidative stress biomarkers, cardiovascular parameters and gut health in obesity

Main Researcher: C. Sánchez-Moreno and B. de Ancos / Start Date: 12/30/2016 / End Date: 12/29/2019 / Institution: AEI/ERDF, EU / Reference number: AGL2016-76817-R
Research Group: Quality and functionality of plant foods (BIOACTIVEG)


PhD Thesis, Master's Thesis and Degree Thesis

Display PhD Thesis, Master's Thesis and Degree Thesis

Tesis Doctoral: Influence of food matrix and processing on the stability, bioaccessibility and metabolism of natural phenolic compounds in a dynamic model of gastrointestinal digestion and colonic fermentation. (2020)

Author: Irene Fernández Jalao / Director: B. de Ancos Siguero, C. Sánchez-Moreno González

Institution: Universidad Complutense de Madrid

Tesis Doctoral: Evaluation of antiinflammatory, antioxidant, and hypolipidemic properties of processed onion as a functional ingredient in vitro and in an animal model. (2017)

Author: Clara Colina Coca / Director: C. Sánchez-Moreno González, B. de Ancos Siguero

Institution: Universidad Complutense de Madrid

Tesis Doctoral: Metabolomic-driven evaluation of processed onion in the prevention of cardiovascular and liver disease in a model of diet-induced hypercholesterolemia (2017)

Author: Diana González Peña / Director: Sánchez-Moreno González, B. de Ancos Siguero

Institution: Universidad Complutense de Madrid