Metabolismo y bioactividad de fitoquímicos (BIOCELL)
Department: Departamento de Metabolismo y Nutrición
Raquel Mateos is qualified in Chemical Sciences BSc (University of Salamanca, Spain, 1995) and Chemical Sciences PhD (University of Seville, Spain, 2002). She developed her Doctoral Thesis in the “Instituto de la Grasa” belonging to the Spanish National Research Council (CSIC) with a FPI fellowship. Virgin olive oil polyphenols are the focus of her PhD thesis, working on their chemical characterization. Afterwards, Dra. Mateos won a 2 years post-doctoral fellowship from the Spanish government at the “Instituto del Frío” from CSIC (2002-2004), to evaluate biological aspects of olive oil polyphenols, including bioavailability and antioxidant activity in cellular models. Dra. Mateos continued her research activity in the Andalusian Institute of Agricultural Research and Training (IFAPA) doing post-doctoral research (2004-2007) until the end of 2007 when she got a permanent position as a Tenured Scientist at IFAPA. Finally, Dra. Mateos came to work at the Institute of Food Science, Technology and Nutrition (ICTAN) belonging to CSIC as a Tenured Scientist, where she is working today. She is a member of the Metabolism and Bioactivity of Phytochemicals (BIOCELL) carrying out basic and applied research to study the health benefits of bioactive compounds. Her research is focused on polyphenols, proceeding from plant-derived foodstuff, evaluating their bioavailability and mechanisms of action through cellular lines and animal models, as well as clinical studies of intervention in humans. The findings have generated more than 100 articles in Peer-Reviewed Journals (h index of 33), 3 international patents, many presentations at national and international scientific conferences and several chapters in text books. She has directed 3 PhD and many MSc Theses. Dra. Mateos medium to long term objectives are the prevention of disease through the consumption of foods rich in bioactive components, studying diverse aspects to widen the understanding of metabolic pathways and biological activity.
Baeza, G., Sarriá, B., Mateos, R., Bravo, L. Improved LC-MSn characterization of hydroxycinnamic acid derivatives and flavanols in mate (Ilex paraguariensis) and evaluation of the polyphenols and methylxanthines content and their antioxidant activity. Food Chem., 241, 232-241 (2018). DOI: 10.1016/j.foodchem.2017.08.085.
Gómez-Juaristi, M., Sarriá, B., Martínez-López, S., Bravo, L., Mateos, R. Flavanol bioavailability in two cocoa products with different phenolic contents. A comparative study in humans. Nutrients 11, 1441 (2019). DOI: 10.3390/nu11071441.
Martínez-López, S., Sarriá, B., Mateos, R., Bravo, L. Moderate consumption of a soluble green/roasted coffee rich in caffeoylquinic acids reduces cardiovascular risk markers: results from a randomized, cross-over, controlled trial in healthy and hypercholesterolemic subjects. Eur. J. Nutr. 58, 865-878 (2019). DOI 10.1007/s00394-018-1726-x.
Eficacy of new products combining hydroxycinnamates and beta-glucans as a dietary tool against obesity and associated dysfunctions (hyperglicaemia and dyslipemia). (OBHEALTH)
Duración: 01/01/2016 – 31/12/2020
IP y co-IP: Laura Bravo Clemente y Raquel Mateos Briz
Entidad Financiadora: Programa Estatal de I+D+I Orientada a los Retos de la Sociedad, Secretaría de Estado de Investigación, Desarrollo e Innovación, MINECO (Cofinanciación FEDER).
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