Phytochemicals, Molecular Mechanisms and Health (PHYTOBIOMOL)
Department: Department of Metabolism and Nutrition
Maria Angeles Martín Arribas is Tenured Scientist at the Institute of Food Science, Technology and Nutrition (ICTAN) of the Spanish National Research Council (CSIC). She obtained her B.S. degree in Biology from the University Complutense of Madrid in 1991 and her Ph.D. in Biochemistry and Molecular Biology from the same university in 1995. She started her research career in the Institute of Biochemistry (IB, CSIC-UCM) and in 2005, she moved to the ICTAN (CSIC). Since 2007, she participates as a Researcher at the Centro de Investigación Biomédicas en Red de Diabetes y Enfermedades Metabólicas Asociadas (CIBERDEM), which brings together 29 top Spanish Research Groups in the field of diabetes and associated diseases. She is currently the Head Researcher of the NUTRALMET (Nutrition and Metabolic Alterations) Group (https://www.ciberdem.org/grupos/grupo-de-investigacion?id=16904) of CIBERDEM.
Her research activity is focused on the study of natural bioactive compounds, mainly polyphenols, with favourable effects against diseases associated with oxidative stress and inflammation, with special attention on diabetes and its complications associated. Her interest is also focused on the characterization of the specific molecular mechanisms involved in the beneficial effects of these compounds including their relationship with gut microbiome and their potential impact in metabolome.
García-Díez E, López-Oliva ME, Pérez-Vizcaíno F, Pérez-Jiménez J, Ramos S, Martín MA*. Dietary Supplementation with a Cocoa–Carob Blend Modulates Gut Microbiota and Prevents Intestinal Oxidative Stress and Barrier Dysfunction in Zucker Diabetic Rats. Antioxidants 12, 1519. (2023). DOI: 10.3390/antiox12081519
García-Díez E, López-Oliva ME, Caro-Vadillo A, Pérez-Vizcaíno F, Pérez-Jiménez J, Ramos S, Martín MA*. Supplementation with a cocoa–carob blend, alone or in combination with metformin, attenuates diabetic cardiomyopathy, cardiac oxidative stress and inflammation in Zucker diabetic rats. Antioxidants 11, 432. (2022) DOI: 10.3390/antiox11020432
Ramos S and Martin MA*. Impact of diet on gut microbiota. Curr Opin Food Sci 37, 83-90 (2021) DOI: 10.1016/j.cofs.2020.09.00
Alvarez-Cilleros D, Ramos S, López-Oliva E, Martín MA*. Preventive effect of cocoa flavanols against glucotoxicity-induced vascular inflammation in the arteria of diabetic rats and on the inflammatory process in TNF-α-stimulated endothelial cells. Food Chem Toxicol 146, 111824 (2020). DOI: 10.1016/j.fct.2020.111824
Alvarez-Cilleros D, Ramos S, López-Oliva E, Escriva F, Alvarez C, Fernandez-Millan E, Martín MA*. Cocoa diet modulates gut microbiota composition and improves intestinal health in Zucker diabetic rats. Food Res Int 132, 109058 (2020). DOI:10.1016/j.foodres.2020.109058
IP y co-IP: Prof. Crisanto Gutiérrez y Josefa González.
Duración: 2023 – 2024
Entidad financiadora: CSIC
Supplementation with Hytolive® for the prevention of diseases associated with aging.
IP y co-IP: Mª Raquel Mateos Briz y Mª Ángeles Martín
Duración: 15 Diciembre de 2023-17 Diciembre de 2024
Entidad financiadora: GENOSA ID, S.L.
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