Home » ICTAN Members » Sonia de Pascual-Teresa Fernandez
Sonia de Pascual-Teresa Fernandez
Tenured Scientist
Research Groups: Polifenoles y salud (POLYHEALTH)
Department: Department of Metabolism and Nutrition
Short Bio
Sonia de Pascual-Teresa has a degree in Pharmacy and a PhD from the University of Salamanca (1999). Since 2003 she has been working at ICTAN –CSIC (formerly Instituto del Frio), first thanks to a Ramón y Cajal contract and since 2007 as a Tenured Scientist. Previously she worked at the Quadram Institute in Norwich (formerly IFR) thanks to a Marie Curie Individual Fellowship and at the University of Reading under a BBSRC grant, UK. From the beginning, her entire career has been developed in the field of dietary polyphenols, first from an analytical point of view and later focusing on their biological activity, moving from biochemical tests, to cell culture models and human trials. In recent years she has focused on demonstrating that dietary nutrients and bioactive compounds are capable of preventing the neurocognitive and cardiometabolic deterioration associated with aging.
- Vauzour, D.; Tejera-Hernandez, N.; O’Neill, C.; Booz, V.; Jude, B.; Wolf, I.; Rigby, N.; Silvan, J.M.; Curtis, P.J.; Cassidy, A.; de Pascual-Teresa, S.; Rimbach, G.; Minihane, A.M. Anthocyanins do not influence long chain n-3 fatty acid status: Studies in cells, rodents and humans. J. Nutr. Biochem. 26(3): 211-218 (2015).
- Mraihi, F.; Hidalgo, M.; de Pascual-Teresa, S.; Trabelsi-Ayadi, M.; Jamila-Kaltoum, C. Wild grown red and yellow hawthorn fruits from Tunisia as source of antioxidants. Arab. J. Chem. 8(4): 570-578 (2015).
- Baenas, N.; Silvan, J.M.; Medina, S.; de Pascual-Teresa, S.; Garcia-Viguera, C.; Moreno, D.A. Metabolism and antiproliferative effects of sulforaphane and broccoli sprouts in human intestinal (Caco-2) and hepatic (HepG2) cells. Phytochem. Rev. 14(6): 1035–1044 (2015).
- Silvan, J.M.; Reguero, M.; de Pascual-Teresa, S. Protective effect of anthocyanins and xanthophylls on UVB-induced damage in retinal pigment epithelial cells. Food Func. 7, 1067-1076 (2016).
- Garcia-Herrera, P.; Perez-Rodriguez, M.L.; Aguilera-Delgado, T.; Lavari-Reyes, M.J.; Olmedilla-Alonso, B.; Camara, M.; de Pascual-Teresa, S. Anthocyanin profile of red fruits and black carrot juices, purees and concentrates by HPLC-DAD-ESI/MS-QTOF. Int. J. Food Sci. Tech. 59, 2290–2300 (2016).
- Pradas del Real, A.; Silvan, J.M.; de Pascual-Teresa, S.; Guerrero, A.; Garcia, P.; Lobo, M.C.; Perez-Sanz, A. Role of the polycarboxylic compounds on the response of Silene vulgaris to chromium. Env. Sci. Pol. Res. 24(6): 5746-5756 (2017).
- Torno, C; Staats, S.; de Pascual-Teresa, S.; Rimbach, G.; Schulza, S. Fatty acid profile is modulated by dietary resveratrol in rainbow trout (Oncorhynchus mykiss). Mar Drugs. 15(8): 252 (2017).
- de Pascual-Teresa, S.; Clifford, M.N. Advances in Polyphenol Research: A J. Agric. Food Chem Virtual Issue. J. Agric. Food Chem 65(37):8093-8095 (2017).
- García-Conesa, M.T.; Chambers, K.; Combet, E.; Pinto, P.; García-Aloy, M.; Andres-Lacueva, C.; de Pascual-Teresa, S.; Mena, P.; Konic-Ristic, A.; Hollands, W.J.; Kroon, P.A.; Rodriguez-Mateos, A.; Istas, G.; Kontogiorgis, C.A.; Rai, D.; Gibney, E.; Morand, C.; Espín, J.C.; González-Sarrías, A. Comparative meta-analysis of the efficacy of ellagitannin- and anthocyanin-containing products at modifying cardiometabolic biomarkers: factors influencing variability of the individual responses. Int. J. Mol. Sci., 19(3), 694; doi:10.3390/ijms19030694 (2018).
- Vauzour, D.; Rodriguez-Ramiro, I.; Rushbook, S.; Ipharraguerre, I.R.; Bevan, D.; Davis, S.; Tejero, N.; Mena, P.; de Pascual-Teresa, S.; Del Rio, D.; Gavrilovic, J.; Minihane, A.M. n-3 fatty acids combined with flavan-3-ols prevent steatosis and liver injury in a murine model of NAFLD. BBA Mol Basis Dis. 1864(1):69-78 (2018).
- Bustos, M.; Rocha-Parra, D.; Sampedro, I.; de Pascual-Teresa, S.; León, A. The influence of different air-drying conditions on bioactive compounds and antioxidant activity of berries. J. Agric. Food Chem. 66(11):2714-2723 (2018).
- Rocha-Parra, D.; Chirife, J.; Zamora, C.; de Pascual-Teresa, S. Chemical characterization of an encapsulated red wine powder and its effects on neuronal cells. Molecules 23 (4), 842; doi:10.3390/molecules23040842 (2018).
- Di Donato, P.; Taurisano, V.; Tommonaro, G.; Pasquale, V.; Silvan-Jimenez, J.M.; de Pascual-Teresa, S.; Poli A.; Nicolaus, B. Biological properties of polyphenols extracts from agro industry’s wastes. Waste Biomass Valor 9 (9), 1567–1578 doi.org/10.1007/s12649-017-9939-4 (2018).
- Olmedilla-Alonso, B.; Estévez-Santiago, R.; Silván, J.M.; Sánchez-Prieto, M.; de Pascual-Teresa, S. Effects of a long-term dietary supplementation with xanthophylls and anthocyanins on lutein and zeaxanthin serum concentrations and macular pigment optical density in postmenopausal women. Nutrients. 10(8), 959. pii: E959. doi: 10.3390/nu10080959 (2018).
- Koistinen, V.M.; Bento da Silva, A.; Abrankó, L.; Low, D.; Garcia Villalba, R.; Tomás Barberán, F.; Landberg, R.; Savolainen, O.; Alvarez-Acero, I.; de Pascual-Teresa, S.; Van Poucke, C.; Almeida, C.; Petrásková, L.; Valentová, K.; Durand, S.; Wiczkowski, W.; Szawara-Nowak, D.; González-Domínguez, R.; Llorach, R.; Andrés-Lacueva, C.; Aura, A.M.; Seppänen-Laakso, T.; Hanhineva1, K.; Manach, C.; Bronze, M.R. Interlaboratory coverage test on plant food bioactive compounds and their metabolites by mass spectrometry-based untargeted metabolomic
- Torno, C; Staats, S.; de Pascual-Teresa, S.; Rimbach, G.; Schulza, S. Fatty acid composition and selected gene-expression in Gilthead sea bream (Sparus aurata) is affected by low-fish oil diets, dietary resveratrol, and holding temperature. Mar Drugs. 16(10), 379 (2018).
- Kühn, G; Pallauf, K.; Schulz, C.; Birringe, M.; Diaz-Rica, B.; de Pascual-Teresa, S.; Rimbach, G. Resveratrol modulates desaturase expression and fatty acid composition of cultured hepatocytes. Frontiers in Nutrition 5: 106 (2018).
- Granda, H.; de Pascual-Teresa, S. Polyphenols interaction with other food components as a mean for their neurological health benefits. J. Agric. Food Chem 66(31):8224-8230 (2018).
- Cittadini, M.C.; Repossi, G.; Albrecht, C.; Di Paola, R.; Miranda, A.R.; de Pascual-Teresa, S.; Soria, E.A. Effects of bioavailable phenolic compounds from Ilex paraguariensis on the brain of mice with lung adenocarcinoma. Phytother Res. 33(4) 1142-1149 (2019).
- Torno, C; Staats, S.; de Pascual-Teresa, S.; Rimbach, G.; Schulza, S. Effects of resveratrol and genistein on growth, nutrient utilization, and fatty acid composition of rainbow trout. Animal 13(5):933-940 (2019).
- Torno, C; Staats, S.; Fickler, A.; de Pascual-Teresa, S.; Izquierdo, M.S.; Rimbach, G.; Schulza, S. Combined effects of nutritional, biochemical and environmental stimuli on growth performance and fatty acid composition of gilthead sea bream (Sparus aurata). PlosOne 14(5):e0216611 (2019).
- Estévez-Santiago, R.; Silván, J.M.; Can-Cauich, C.A.; Veses, A.M.; Alvarez-Acero, I.; Martinez-Bartolome, M.A.; San Román R.; Olmedilla-Alonso, B.; de Pascual-Teresa, S. Lack of a Synergistic Effect on Cardiometabolic and Redox Markers in a Dietary Supplementation with Anthocyanins and Xanthophylls in Postmenopausal Women. Nutrients, 11(7), 1533226 (2019).
- Eker, M.E.; Kjersti, A.; Budic-Leto, I.; Rimac-Brncic, S.; El, S.N.; Karakaya, S.; Simsek, S.; Manach, C.; Wiczkowski, W.; de Pascual-Teresa, S. A review of factors affecting anthocyanin bioavailability: possible implications for the interindividual variability. Foods 9(1):2 (2020).
- Fischer, A.; Lüersen, K.; Schultheiß, G.; de Pascual-Teresa, S.; Ipharraguerre, I. R.; Mereu, A.; Rimbach, G. Supplementation with nitrate modestly affects lipid and glucose metabolism in genetic (db/db) and dietary-induced murine models of obesity. J Clin Biochem Nutr 66(1):1-12 (2020).
- Suarez, L.; Benavente-Ferraces, I.; Plaza, C.; de Pascual-Teresa, S.; Suarez-Ruiz, I.; Centerno, T.A. Hydrothermal carbonization as a sustainable strategy for integral valorisation of apple waste. Bioresource Technology, 309 (2020) https://doi.org/10.1016/j.biortech.2020.123395
- Ruskovska, T.; Massaro, M.; Carluccio, M.A.; Arola-Arnal, A.; Muguerza Marquínez, B.; Vanden Berghe, W.; Declerck, K.; Bravo Vázquez, F.I.; Calabriso, N.; Combet, E.; Gibney, E.R.; Gomes, A.; Gonthier, M.P.; Kistanova, E.; Krga, I.; Mena, P.; Morand, C.; Nunes dos Santos, C.; de Pascual-Teresa, S.; Rodriguez-Mateos, A.; Scoditti, E.; Suárez Recio, M.; Milenkovic, D. Systematic bioinformatic analysis of nutrigenomic data of flavanols in cell models of cardiometabolic disease. Food & Func. 11(6): 5040-5064 (2020).
- Pallauf, K.; Günther, I.; Kühn, G.; Chin, D.; de Pascual-Teresa, S.; Rimbach, G. Can resveratrol be considered as caloric restriction mimetic? – Insights from studies in mice. Adv. Nutr, in press (2021).
- Chamorro, S.; Cueva-Mestanza, R.; de Pascual-Teresa, S. Effect of spray drying on the polyphenolic compounds present in purple sweet potato roots: Identification of new cinnamoylquinic acids. Food Chem., in press (2021).
- Foods rich in polyphenols as a healthy and sustainable strategy for healthy aging (KEPHENOL). PI: Sonia de Pascual-Teresa. 01/07/2020 – 30/06/2024. MIC. (PID2019-107009RB-I00).
- Determination of bile acids in fluids and tissues of different species. Sonia de Pascual-Teresa. 2020-2021. IGMAZEN CONSULTING, S.L. Industry Sponsored Research.
- Dietary anthocyanins and flavanols from food as a strategy for healthy aging: cardiovascular health and cognitive status (POLYAGE). PI: Sonia de Pascual-Teresa. 30/12/2016 – 31/12/2020. MINECO. AGL2016-76832-R.
- Actividad de polifenoles de vino liofilizado procedente de excedentes: efecto sobre microbiota e influencia en inflamación y enfermedad cardiovascular. Investigador principal: Sonia de Pascual-Teresa Fernández. 01/01/2016 – 31/12/2018. CSIC-EMHE. (MHE-200007)
- Determinación de ácidos grasos en fluidos biológicos, tejidos y piensos animales de especímenes alimentados con distintos piensos enriquecidos con polifenoles. Sonia de Pascual-Teresa Fernández. 2015-2016.University of Kiel. Apoyo tecnológico.
- Interindividual variation in response to comsuption of plant food bioactives and determinants involved (POSITIVe). Investigador responsable: Christine Morand (INTA, Clermont-Ferrand, Francia). 2014-2018. COST ACTION FA1403.
- Antocianos y xantofilas: fuentes, mecanismos de accion y efectos en humanos (PIGMENTHEALTH). Investigador principal: Sonia de Pascual-Teresa Fernández. 01/02/2013-31/01/2016. MINECO. AGL2012-30803.
- Polyphenols and carotenoids as enhancers of omega-3 fatty acid status and bioactivity. Investigador principal: Sonia de Pascual-Teresa Fernández. 01/01/2013-31/12/2014. CSIC I-LINK0502.
- Caracterización y evaluación funcional y de seguridad de compuestos bioactivos de frutas iberoamericanas como ingredientes alimentarios. Investigador principal: Diego A. Moreno Fernández. 01/01/2012-31/12/2015. Programa Iberoamericano de Ciencia y Tecnología para el Desarrollo (CYTED). Linea de investigación 1.3. Identificación, evaluación, producción y seguridad de compuestos bioactivos de origen natural como ingredientes alimentarios.
- Aplicación de un método de determinación de polifenoles en distintos tejidos animales. Investigador principal: Sonia de Pascual-Teresa Fernández. 1/06/2013-30/09/2013. LUCTA. Contrato Industria.
915492300 ext.: 231309
s.depascualteresa@csic.es
ORCID:
0000-0001-8546-8507
Researcher ID:
F-5321-2011